Complex GERD: Identifying the challenges and finding the solutions

Complex GERD: Identifying the challenges and finding solutions
Webcast of the meeting held Sunday, October 25, 2009 – San Diego, CA

Post Test

  1. Symptoms can recur in GERD patients taking PPI maintenance therapy. What is the percentage of patients experiencing breakthrough symptoms?

    <10%

    11%–20%

    21%–30%

    >30%

  2. For patients on PPI medication who experience breakthrough heartburn, when is this most likely to occur?

    In the morning

    In the middle of the day

    At night

    Any time of the day

  3. Dexlansoprazole MR maintains intragastric pH >4 for _______ hours?

    12 hours

    15 hours

    17 hours

    20 hours

    None of the above

  4. The prevalence of symptomatic gastroesophageal reflux disease (GERD) appears to be increasing. Which of the following factors is the most likely cause?

    Increasing tobacco use

    Increasing prevalence of obesity

    Increasing alcohol use

    All of the above

    None of the above

  5. Which of the following statements regarding GERD in older patients is correct?

    Older patients with GERD experience increased severity of esophagitis

    Older patients with GERD have a decreased risk of Barrett’s esophagus

    Older patients with GERD appear to have higher incidence of typical GERD symptoms

    All of the above

    None of the above

  6. The recent study published in the Lancet by O’Donoghue et al looking at the clinical efficacy of clopidogrel with or without a PPI found:

    All cause death was higher in those patients taking a PPI

    A higher percentage of patients taking a PPI experienced an MI

    There is no evidence to support the need to avoid concomitant use of PPIs when taking clopidogrel

    None of the above

  7. Which of the following statements regarding GERD and IBS is incorrect?

    GERD is seen in all patients with IBS

    GERD patients with co-morbid IBS have less severe reflux symptoms than GERD patients without co-morbid IBS

    GERD patients without co-morbid IBS have worse GERD-related quality of life than GERD patients with co-morbid IBS

    All of the above

    None of the above

  8. Visceral hypersensitivity may provide a unifying hypothesis for overlapping upper and lower GI symptoms. True or false?

    True

    False

  9. Which of the following statements is correct?

    Tricyclic antidepressants improve IBS symptoms but have no effect on esophageal symptoms

    Dexlansoprazole MR has a significant effect on daytime and night-time heartburn in NERD patients as compared to placebo

    Laxatives improve global symptoms in patients with IBS-C

    None of the above

    All of the above